| Item Type | Name |
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Academic Article
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Simultaneous RP-HPLC-DAD quantification of bromocriptine, haloperidol and its diazepane structural analog in rat plasma with droperidol as internal standard for application to drug-interaction pharmacokinetics.
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Academic Article
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Biochemical and docking analysis of substrate interactions with polyisoprenylated methylated protein methyl esterase.
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Academic Article
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d-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens.
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Academic Article
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Evaluation of the behavioral and pharmacokinetic profile of SYA013, a homopiperazine analog of haloperidol in rats.
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Academic Article
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Multi-receptor drug design: Haloperidol as a scaffold for the design and synthesis of atypical antipsychotic agents.
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Academic Article
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Small diverse antioxidant functionalities for oxidative stress disease drug discovery.
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Academic Article
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Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants.
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Academic Article
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Polyisoprenylated methylated protein methyl esterase: a putative biomarker and therapeutic target for pancreatic cancer.
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Academic Article
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Further evaluation of the tropane analogs of haloperidol.
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Academic Article
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Structure-activity relationship (SAR) and preliminary mode of action studies of 3-substituted benzylthioquinolinium iodide as anti-opportunistic infection agents.
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Academic Article
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Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors.
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Academic Article
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Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands.
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Academic Article
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Detection of a neurotoxic quaternary pyridinium metabolite in the liver of haloperidol-treated rats.
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Academic Article
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New analogs of SYA013 as sigma-2 ligands with anticancer activity.
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Academic Article
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Systemic antifungal agents against AIDS-related opportunistic infections: current status and emerging drugs in development.
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Academic Article
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Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species.
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Concept
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Calcimycin
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Concept
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Acetyl-CoA Carboxylase
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Concept
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Acrylamides
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Concept
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Cyclic AMP
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Concept
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Adrenergic alpha-Antagonists
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Concept
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Alkaloids
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Concept
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Amides
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Concept
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Amines
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Concept
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Quaternary Ammonium Compounds
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Concept
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Amylose
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Concept
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Anti-Infective Agents
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Concept
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Anti-Bacterial Agents
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Concept
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Antidepressive Agents
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Concept
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Antifungal Agents
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Concept
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Antimalarials
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Concept
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Antineoplastic Agents
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Concept
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Antioxidants
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Concept
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Antiparasitic Agents
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Concept
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Antiprotozoal Agents
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Concept
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Apomorphine
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Concept
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Azepines
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Concept
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Benzodiazepines
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Concept
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Binding Sites
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Concept
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Biological Products
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Concept
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Bromocriptine
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Concept
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Butanones
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Concept
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Butyrophenones
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Concept
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Calcium
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Concept
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Carbolines
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Concept
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Carboxylic Ester Hydrolases
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Concept
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Carrier Proteins
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Concept
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Cisplatin
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Concept
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Clozapine
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Concept
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Collagen
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Concept
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Dose-Response Relationship, Drug
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Concept
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Droperidol
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Concept
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Drug Interactions
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Concept
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Drug Screening Assays, Antitumor
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Concept
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Drug Stability
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Concept
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Fatty Acids
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Concept
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Haloperidol
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Concept
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Hypoglycemic Agents
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Concept
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Imidazoles
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Concept
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Indenes
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Concept
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Indicators and Reagents
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Concept
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Indoles
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Concept
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Iodine Radioisotopes
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Concept
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Isoquinolines
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Concept
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Ligands
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Concept
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Nitrogen
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Concept
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Oxalates
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Concept
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Piperazines
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Concept
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Piperidines
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Concept
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Platelet Aggregation Inhibitors
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Concept
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Protein Methyltransferases
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Concept
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Pyridines
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Concept
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Pyridinium Compounds
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Concept
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Pyrrolidines
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Concept
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Quinolines
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Concept
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Quinolinium Compounds
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Concept
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Receptors, Dopamine
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Concept
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Receptors, Serotonin
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Concept
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Reference Standards
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Concept
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Serotonin Antagonists
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Concept
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Stereoisomerism
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Concept
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Sulfhydryl Compounds
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Concept
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Thioxanthenes
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Concept
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Thrombin
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Concept
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Antipsychotic Agents
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Concept
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Tropanes
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Concept
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Vasodilator Agents
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Concept
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1-Methyl-3-isobutylxanthine
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Concept
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Drug Design
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Concept
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Dopamine Agents
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Concept
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Molecular Probes
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Concept
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1-Methyl-4-phenylpyridinium
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Concept
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Arachidonic Acid
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Concept
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Receptors, Dopamine D2
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Concept
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Receptors, sigma
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Concept
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Dopamine Agonists
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Concept
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Dopamine Antagonists
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Concept
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Indole Alkaloids
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Concept
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Tetrahydroisoquinolines
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Concept
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Receptor, Serotonin, 5-HT1A
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Concept
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Receptor, Serotonin, 5-HT2B
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Concept
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Phenylcarbamates
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Concept
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Serotonin Plasma Membrane Transport Proteins
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Concept
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Receptors, Dopamine D4
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Concept
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Benzothiazoles
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Concept
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Small Molecule Libraries
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Concept
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Drug Discovery
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Academic Article
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A study of the structure-affinity relationship in SYA16263; is a D2 receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice?
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Academic Article
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New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263.
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Academic Article
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Design and discovery of a high affinity, selective and ?-arrestin biased 5-HT7 Receptor Agonist.
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